BC Advantage - 2026 Issue 4

Medical Coding: Mononucleosis

Mononucleosis (infectious mononucleosis), commonly referred to as “mono,” is a viral infection most often caused by the Epstein–Barr virus (EBV). It is frequently seen in adolescents and young adults and is characterized by fatigue, fever, sore throat, and lymphadenopathy. For medical coders, accurate reporting requires careful review of the physician documentation, correct ICD-10-CM code selection, and attention to related manifestations or complications. Understanding Mononucleosis Infectious mononucleosis is primarily transmitted through saliva, which is why it is sometimes referred to as the “kissing disease.” The infection can cause systemic symptoms and may involve multiple body...

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