Multiple Molecular Marker Array-Based Evaluation (January 2006)

January 2006 pages 5-6 Coding Communication:Multiple Molecular Marker Array-Based Evaluation Knowledge of the role that genetic mutations play in neoplastic and non-neoplastic disease together with the number of implicated genetic aberrations continues to increase, driven, in part, by new analytic methods. One of these is arraybased technology, which provides a platform that is rapidly advancing the study of molecular diagnostic abnormalities associated with a number of different diseases. Results from this testing are used to interpret, diagnose, and monitor disease states and to direct therapeutic intervention. They may also identify preclinical and carrier states to identify patients predisposed to...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This CPT Assistant article provides background on array-based molecular marker evaluation and how the newer CPT code series relates to broader molecular diagnostics reporting. It is intended for coding professionals, pathology/laboratory staff, and clinicians who work with genetic and molecular testing. The article covers the scope of the code series, related specimen preparation and ancillary services, the distinction from other molecular diagnostic reporting, and illustrative clinical examples.

Why This Topic Matters

Array-based genetic testing introduced new reporting considerations for physician work, laboratory involvement, and related preparatory services. Understanding the article helps readers identify where this CPT code series fits within molecular pathology reporting and why it differs from other molecular diagnostic code groups.

Article Sections

  1. Coding Communication: Multiple Molecular Marker Array-Based Evaluation

    Introduces array-based molecular testing and explains the general purpose of the new CPT code series. It also summarizes how the article frames related specimen preparation and ancillary molecular diagnostic services.

  2. Array-Based Evaluations vs Molecular Diagnostics

    Compares the array-based evaluation code series with the broader molecular diagnostics section of CPT. It discusses the relationship between these code families and the general role of interpretation and reporting within this context.

  3. Multiple Molecular Marker Array-Based Evaluations

    Describes the kinds of clinical situations in which array-based evaluations may be used. It provides broad examples across disease categories and introduces the article’s illustrative coding scenarios.

  4. Clinical Example: Code 88385

    Presents a detailed pathology example involving array-based evaluation in an oncology setting. The example illustrates the broader workflow and documentation elements discussed in the article.

  5. Clinical Example: Code 88386

    Presents a second clinical example involving array-based evaluation and genomic testing in a hematology/oncology context. The example shows another use of the article’s general coding framework.

What You Will Learn

  • How the article positions array-based molecular marker evaluation within CPT
  • How the article distinguishes array-based evaluation from broader molecular diagnostics reporting
  • What types of clinical contexts are discussed for array-based testing
  • What broad service components are addressed in the article
  • How the article uses clinical examples to illustrate array-based evaluation scenarios

Who Should Read This

  • Medical coders
  • Pathologists
  • Laboratory professionals
  • Oncology billing staff
  • Molecular diagnostics staff
  • Clinical documentation specialists

Codes Discussed

Code Ranges Discussed


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