AHA Coding Clinic® for HCPCS - 2025 Issue 2; For Your Information

New, deleted and revised CPT Proprietary Laboratory Analyses (PLA) codes effective July 1, 2025

The most recent changes to the CPT PLA codes include 23 additions, 6 deletions, and 1 revision. New CPT PLA codesCPT Code Long Descriptor Effective Date 0552U Reproductive medicine (preimplantation genetic assessment), analysis for known genetic disorders from trophectoderm biopsy, linkage analysis of disease causing locus, and when possible, targeted mutation analysis for known familial variant, reported as low-risk or high-risk for familial genetic disorder July 1, 2025 0553U Reproductive medicine (preimplantation genetic assessment), analysis of 24 chromosomes using DNA genomic sequence analysis from embryonic trophectoderm for structural rearrangements, aneuploidy, and a mitochondrial DNA score, results reported as...

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