AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 2; Ask the Editor

Chemotherapy Desensitization

A patient with advanced-stage right ovarian carcinoma and peritoneal metastasis required chemotherapy desensitization. The patient is status post nine cycles of adjuvant chemotherapy; however, the patient developed anaphylaxis during the last two infusions and was referred to allergy/immunotherapy providers for chemotherapy desensitization. During the admission, the patient was given chemotherapy incrementally, increasing the dosage under medical supervision. What is the appropriate principal diagnosis when the patient is desensitized to chemotherapy during the admission? Is code Z51.6, Encounter for desensitization to allergens, appropriate for this case? ...

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