AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 4; New/Revised ICD-10-CM Codes
Familial Hypercholesterolemia
Code E78.01, Familial hypercholesterolemia, was expanded to create new codes to identify Homozygous familial hypercholesterolemia [HoFH] (E78.010), Heterozygous familial hypercholesterolemia [HeFH] (E78.011), and Familial hypercholesterolemia, unspecified (E78.019). Familial hypercholesterolemia is an inherited genetic disorder that interferes with the body’s ability to remove low-density lipoprotein cholesterol (LDL-C), the “bad cholesterol” from the blood. LDL-C causes blockage in the arterial wall and narrows the lumens, which increases the risk of coronary heart disease, acute myocardial infarction, and stroke. There are two types of familial hypercholesterolemia: heterozygous and homozygous. Heterozygous familial hypercholesterolemia (HeFH) occurs...
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Article Overview
This article explains familial hypercholesterolemia as an inherited lipid disorder and discusses how the condition is divided into clinically distinct forms. It is relevant for coding professionals, clinical documentation teams, and cardiology-related practices because it summarizes the condition, common presentations, and the ICD-10-CM update that created separate identifiers for the main categories. The article also touches on treatment approaches and the broader clinical significance of accurate subtype reporting.
Why This Topic Matters
Accurate documentation of familial hypercholesterolemia subtype affects medical coding, data quality, and clinical reporting for a condition associated with serious cardiovascular risk.
What You Will Learn
- How familial hypercholesterolemia is generally characterized
- The major clinical subtypes discussed in the article
- Why the ICD-10-CM update matters for documentation and reporting
- Broad treatment approaches mentioned for affected patients
Who Should Read This
- Medical coders
- Clinical documentation specialists
- Physicians
- Cardiology and primary care staff
- Health information management professionals
Codes Discussed
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