Reporting Multianalyte Assay With Algorithmic Analysis Codes 81515 and 81558

Why This Topic Matters

MAAA reporting can be difficult because code selection depends on matching the performed analysis to the CPT descriptor and, when applicable, the proprietary test named in the code set. This article helps readers identify the relevant CPT 2025 updates and understand the overall scope of the laboratory and transplant-related guidance covered by the premium content.

Article Sections

1. June 2025 pages 1-16

   Publication and page information for the article.

2. Pathology and Laboratory

   General laboratory coding context for the article’s discussion of multianalyte assay reporting.

3. Multianalyte Assays with Algorithmic Analyses

   Overview of the new CPT 2025 MAAA reporting topics discussed in the article, including the broad laboratory and transplant areas involved.

4. Clinical Example (81515)

   A representative clinical scenario associated with one of the discussed laboratory codes.

5. Description of Procedure (81515)

   A procedural outline for the same laboratory scenario, presented at a high level.

6. Clinical Example (81558)

   A representative clinical scenario associated with the transplant-related laboratory code discussed in the article.

7. Description of Procedure (81558)

   A procedural outline for the transplant-related laboratory scenario, presented at a high level.