Genomic Sequencing Procedure for Severe Inherited Conditions (81443) (November 2018)

November 2018 page 9 Genomic Sequencing Procedure for Severe Inherited Conditions (81443) For Current Procedural Terminology (CPT®) 2019, a new genomic sequencing procedure (GSP) code (81443) has been added for a test that analyzes 15 genes associated with multiple severe inherited conditions. This screening test yields important information that may be used in prenatal genetic counseling to determine if an individual is a carrier for a number of severe inherited conditions. Genomic Sequencing Procedures and Other Molecular Multianalyte Assays I81443Genetic testing for severe inherited conditions (eg, cystic fibrosis, Ashkenazi Jewish-associated disorders [eg, Bloom syndrome, Canavan disease, Fanconi anemia...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This CPT Assistant article from November 2018 discusses a new genomic sequencing procedure code introduced for screening related to severe inherited conditions. It is intended for coding professionals, laboratory teams, and genetics-focused clinicians who need to understand the scope of the CPT update, the related parenthetical notes, and the broader molecular pathology context referenced in the article.

Why This Topic Matters

The article helps readers recognize when the CPT update affects carrier screening and related genetic testing workflows. It also places the new code in the context of other molecular pathology codes and related tests so users can compare the general subject matter covered by the guidance.

Article Sections

  1. November 2018 page 9

    Introductory article header and publication context for the CPT update.

  2. Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

    Overview of the new genomic sequencing procedure code and its relationship to other molecular testing categories. The section also discusses the broader setting in which the code update appears.

  3. Coding Tip

    General coding guidance on how certain molecular pathology analyte procedures are organized across Tier 1, Tier 2, and unlisted reporting categories.

  4. Clinical Example (81443)

    A representative clinical scenario showing the type of patient context associated with the code update and the related testing workflow.

  5. Description of Procedure (81443)

    A procedural overview of laboratory and reporting steps associated with the testing process described in the article.

What You Will Learn

  • What the article says about the CPT 2019 genomic sequencing procedure update
  • How the article frames the code within broader molecular pathology guidance
  • What kinds of related parenthetical notes and supporting context are discussed
  • What clinical and procedural context the article uses to illustrate the testing scenario

Who Should Read This

  • Medical coders
  • Coding auditors
  • Genetics laboratory staff
  • Pathologists
  • Prenatal genetic counseling staff
  • Obstetrics and gynecology practices

Codes Discussed

Code Ranges Discussed


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