Pathology and Laboratory: Tier 2 Molecular Pathology Procedures (Q & A) (July 2013)

July 2013 page 12 Pathology and Laboratory: Tier 2 Molecular Pathology Procedures Question: If a lab performs a single nucleotide polymorphism test (SNP) that is not one of the tests listed under code 81400 Molecular pathology procedure, Level 1(eg, identification of single germline variant [eg, SNP] by techniques such as restriction enzyme digestion or melt curve analysis), is it okay to report this code? Answer: No. The Tier 2 molecular pathology codes (81400-81408) cannot be self-assigned to genetic tests. The only tests for which these codes may be reported with codes in this series are the tests listed under...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains a CPT molecular pathology coding question from July 2013 and clarifies how Tier 2 molecular pathology procedures are addressed in the CPT code set and related AMA guidance. It is relevant to pathology and laboratory coding professionals who need to understand the scope of the Tier 2 molecular pathology series, the limits of self-assignment, and how an unlisted molecular pathology procedure is handled at a high level.

Why This Topic Matters

Accurate reporting in molecular pathology depends on knowing which tests are included in the CPT-listed families and which fall outside the structured Tier 2 series. This article helps coders and billing staff identify when additional guidance or an unlisted procedure category is involved.

Article Sections

  1. July 2013 page 12

    A dated Q&A discussion from CPT Assistant focused on molecular pathology reporting guidance. The section addresses a coding question within pathology and laboratory services.

What You Will Learn

  • How Tier 2 molecular pathology procedures are discussed in a CPT Q&A format
  • The relationship between listed CPT molecular pathology tests and unlisted molecular pathology procedures
  • The role of AMA/CPT guidance in supporting molecular pathology coding decisions
  • How the article frames a question about an SNP test in the context of molecular pathology reporting

Who Should Read This

  • Medical coders
  • Pathology and laboratory billing staff
  • Compliance teams
  • Revenue cycle professionals
  • Coding educators

Codes Discussed

Code Ranges Discussed


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