Molecular Pathology Update (January 2015)

January 2015 pages 3-7 Molecular Pathology Update The American Medical Association (AMA) established the molecular pathology codes in 2012. Several changes were made to allow for better utilization of this section of codes in the 2015 Current Procedural Terminology (CPT®) code set, of which the most significant are noted below: The Molecular Pathology Gene Table was revised to include claim designators for Tier 2 molecular pathology codes. A new subsection, Genomic Sequencing Procedures and Other Molecular Multianalyte Assays, was added in the Pathology and Laboratory section. Molecular Pathology Information on the AMA CPT Website To assist users in...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article reviews January 2015 updates to the CPT molecular pathology section, including new terminology, revised gene table guidance, expanded genomic sequencing procedure categories, and changes to multianalyte assays with algorithmic analyses. It is aimed at coding professionals, laboratory billing staff, and others who need to understand how the 2015 CPT structure and related publishing timelines were updated. The article also discusses where related code information is published and how the updated section is organized.

Why This Topic Matters

These updates affect how molecular pathology and related genomic testing services are organized in CPT and how users locate current code information. Understanding the scope of the changes is important for accurate claims preparation, reference use, and staying aligned with the 2015 code set structure.

Article Sections

  1. January 2015 pages 3-7

    Introduces the article and places it within the January 2015 CPT Assistant issue.

  2. Molecular Pathology Update

    Summarizes the major 2015 changes to molecular pathology content in CPT and explains the broad areas affected.

  3. Molecular Pathology Information on the AMA CPT Website

    Describes where updated molecular pathology-related code information is published and outlines the publication timeline.

  4. New Definitions

    Provides updated terminology used in CPT reporting for several genetics and molecular pathology concepts.

  5. Molecular Pathology Gene Table

    Explains the role of the gene table in Tier 2 molecular pathology reporting and notes the 2015 table revision.

  6. Tier 1 Molecular Pathology Procedures

    Reviews 2015 updates affecting Tier 1 molecular pathology procedures and related reporting guidance.

  7. Tier 2 Molecular Pathology Procedures

    Covers 2015 revisions to Tier 2 molecular pathology procedures and the scope of the changes to listed analytes.

  8. Genomic Sequencing Procedures and Other Molecular Multianalyte Assays

    Describes the newly created genomic sequencing and multianalyte assay section, including general guidance on panel-based reporting.

  9. Multianalyte Assays with Algorithmic Analyses

    Summarizes the MAAA section, where these procedures are located in CPT, and the 2015 additions and updates.

What You Will Learn

  • How the 2015 CPT molecular pathology section was reorganized
  • Where AMA publishes updated molecular pathology and related code information
  • The general purpose of revised molecular terminology used in CPT reporting
  • How the molecular pathology gene table supports Tier 2 reporting
  • The broad categories of Tier 1, Tier 2, genomic sequencing, and MAAA updates
  • How the CPT article groups panel-based genomic testing and algorithmic assay content

Who Should Read This

  • Medical coders
  • Laboratory billing staff
  • Pathology practices
  • Molecular diagnostics laboratories
  • Revenue cycle professionals

Codes Discussed

Code Ranges Discussed


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