Pathology and Laboratory: Tier 1 Molecular Pathology Procedures (Q&A) (June 2012)

June 2012 page 16 Pathology and Laboratory: Tier 1 Molecular Pathology Procedures Question: A celiac genetic test is performed using high resolution, which exams 35 allele families of the locus DQA1 and 37 allele families of the DQB1 locus. Would it be appropriate to report CPT code 81382? Answer: Yes. Code 81382 is appropriate, and it should be reported once for each locus tested. In this case, 2 units of code 81382 should be reported: once for the DQA1 locus and once for the DQB1 locus. CPT 2012 indicates the following descriptor for code 81382: 81382 HLA Class II...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains a CPT Assistant question-and-answer discussion about molecular pathology coding for HLA testing in the Tier 1 HLA code range. It is relevant to pathology and laboratory coders who need to understand the scope of the HLA code set, the distinction between locus-based and allele-based reporting, and how the June 2012 guidance frames use of the related CPT codes in high-resolution testing contexts.

Why This Topic Matters

The article helps coders and billing staff recognize how HLA molecular pathology procedures are organized within the CPT framework and how the June 2012 guidance addressed reporting for multi-locus testing. It is useful for reducing coding ambiguity in pathology and laboratory workflows that involve HLA typing.

Article Sections

  1. June 2012 page 16

    A dated page reference for the CPT Assistant Q&A content. It situates the article within the June 2012 issue and page location.

What You Will Learn

  • How the article frames Tier 1 molecular pathology HLA testing
  • How the HLA molecular pathology code set is organized
  • How the June 2012 CPT Assistant discussion presents locus-based reporting concepts
  • What types of HLA testing scenarios the article addresses at a general level

Who Should Read This

  • Medical coders
  • Pathology and laboratory billing staff
  • Coding educators
  • Compliance staff
  • Molecular pathology practices

Codes Discussed

Code Ranges Discussed


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