Coding Update: Reporting UGT1A1 Gene Analysis (April 2020)

April 2020 page 9 Coding Update: Reporting UGT1A1 Gene Analysis Several revisions were made in the Genomic Sequencing Procedures subsection within the Pathology and Laboratory section of the Current Procedural Terminology (CPT®) 2020 code set. These changes reflect the dynamic nature of the advances made in genetic analyses and are intended to add greater specificity to the genetic tests available within the gene-specific and genomic Tier 1 and Tier 2 molecular pathology procedures. This coding update provides information about these revisions. Tier 1 Molecular Pathology Procedures  81350UGT1A1 (UDP glucuronosyltransferase 1 family, polypeptide A1) (eg, drug metabolism, hereditary unconjugated...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This coding update article explains a CPT 2020 revision affecting UGT1A1 gene analysis within the genomics and molecular pathology portion of the CPT code set. It is aimed at coding professionals, laboratory staff, and other readers who track CPT changes in genetic testing. The article places the update in clinical context, discusses the associated laboratory workflow at a high level, and describes the kinds of genetic-testing scenarios referenced by the revised guidance.

Why This Topic Matters

Updates in molecular pathology coding can affect how genetic tests are reported and understood across laboratories and clinical practices. This article helps readers identify a revised CPT area and understand the general testing contexts discussed in connection with the change.

Article Sections

  1. April 2020 page 9

    Introduces the coding update and frames the discussion within a specific CPT 2020 publication page.

  2. Tier 1 Molecular Pathology Procedures

    Discusses the Tier 1 molecular pathology context and the revision described for a gene-specific analysis within the CPT 2020 code set.

  3. Tier 2 Molecular Pathology Procedures

    Discusses the Tier 2 molecular pathology context and the revision described for a full-gene analysis within the CPT 2020 code set.

  4. Clinical Example (81350)

    Presents a high-level clinical scenario illustrating the testing context associated with the revised code.

  5. Description of Procedure (81350)

    Summarizes the general laboratory workflow and reporting process described for the example case.

What You Will Learn

  • How a CPT 2020 genomic sequencing update is framed in the article
  • Which parts of molecular pathology coding are discussed
  • What clinical and laboratory contexts are associated with the update
  • How the article presents a representative testing scenario and procedural overview

Who Should Read This

  • Medical coders
  • Pathology and laboratory professionals
  • Genetic testing staff
  • Coding educators and auditors

Codes Discussed


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