Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Update (April 2016)

April 2016 page 4 Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Update Several new codes were added and several codes were revised in the Genomic Sequencing and Other Molecular Multianalyte Assays subsection of the Current Procedural Terminology (CPT®) 2016 code set. The code additions and revisions were made to reflect current clinical practice. Sequencing of fewer than the minimum number of genes indicated in the code descriptor would not be reportable with these codes. Genomic sequencing procedures (GSPs) and other molecular multianalyte assays are DNA or RNA sequence analysis methods that assay multiple genes or genetic regions...

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Note:  The following article synopsis was NOT provided by the AMA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article explains April 2016 updates to CPT genomic sequencing procedures and other molecular multianalyte assay coding. It is aimed at coders, billing staff, and clinical laboratories that report molecular pathology services and need to understand which panel categories were revised, what broad changes were made, and how the update discusses reporting in relation to current CPT structure.

Why This Topic Matters

Molecular pathology coding changes can affect service reporting, charge capture, and compliance for laboratories and practices that perform multigene testing. This update helps readers identify which CPT panel areas were changed and what kinds of guidance accompany the revisions.

Article Sections

  1. Genomic Sequencing Procedures and Other Molecular Multianalyte Assays Update

    Overview of April 2016 CPT changes affecting genomic sequencing procedures and other multianalyte assay reporting. Introduces the scope of the update and the general reason the code set was revised.

  2. Coding Tip

    A short coding note accompanying the update. Presents a general reporting consideration related to the revised code set.

  3. Revision Notes

    Summary discussion of which panel groups were revised and the type of clarifications made. Also notes broader wording changes and comments about the examples used in descriptors.

What You Will Learn

  • The scope of the April 2016 CPT update for genomic sequencing and multianalyte assay reporting
  • Which broad panel categories were added or revised
  • How the article frames reporting relationships among genomic sequencing procedures, Tier codes, and unlisted molecular pathology services
  • What general clarifications were made to panel-based targeted genomic sequence analysis codes

Who Should Read This

  • Medical coders
  • Billing specialists
  • Molecular pathology laboratories
  • Compliance staff
  • Clinical genetic testing practices

Codes Discussed


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