Leukocyte Adhesion Deficiency

Code D71, Functional disorders of polymorphonuclear neutrophils, was expanded and code D71.1, Leukocyte adhesion deficiency, was created to identify leukocyte adhesion deficiency (LAD), a rare genetic disorder that is a combined B cell and T cell immunodeficiency disorder. With this deficiency, the white blood cells, or leukocytes, are unable to effectively adhere to and migrate to sites of infection. This is caused by a lack of certain proteins or adhesion molecules on their surface that are necessary for them to attach to the walls of blood vessels and then migrate to the site of infection.Patients typically present...

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Note:  The following article synopsis was NOT provided by the AHA. It was created by Find-A-Code/innoviHealth.

Article Overview

This article covers leukocyte adhesion deficiency as a rare inherited immunodeficiency and places it within updated ICD-10-CM classification changes for disorders of polymorphonuclear neutrophils. It is relevant for coding professionals, clinical documentation staff, and immunology or infectious disease audiences who need to understand the scope of the diagnostic category and related subtype distinctions.

Why This Topic Matters

The topic matters because diagnosis coding for rare immune disorders can affect accurate recordkeeping, reporting, and downstream clinical or administrative use. The article also helps readers understand how a broader diagnostic family was revised to accommodate more specific functional neutrophil disorders.

What You Will Learn

  • How leukocyte adhesion deficiency fits into the broader diagnostic grouping for polymorphonuclear neutrophil disorders.
  • How the article situates major leukocyte adhesion deficiency subtypes within the condition overview.
  • What other functional neutrophil disorder categories are included alongside leukocyte adhesion deficiency.
  • What kinds of clinical features and management themes are discussed at a high level.

Who Should Read This

  • Medical coders
  • Coding auditors
  • Clinical documentation specialists
  • Immunology clinicians
  • Infectious disease clinicians
  • Healthcare revenue cycle staff

Codes Discussed

  • ICD-10-CM: D71
  • ICD-10-CM: D71.1
  • ICD-10-CM: D71.8
  • ICD-10-CM: D71.9

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