AHA Coding Clinic® for ICD-10-CM and ICD-10-PCS - 2025 Issue 4; New/Revised ICD-10-CM Codes

Leukocyte Adhesion Deficiency

Code D71, Functional disorders of polymorphonuclear neutrophils, was expanded and code D71.1, Leukocyte adhesion deficiency, was created to identify leukocyte adhesion deficiency (LAD), a rare genetic disorder that is a combined B cell and T cell immunodeficiency disorder. With this deficiency, the white blood cells, or leukocytes, are unable to effectively adhere to and migrate to sites of infection. This is caused by a lack of certain proteins or adhesion molecules on their surface that are necessary for them to attach to the walls of blood vessels and then migrate to the site of infection.Patients typically present...

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