AMA CPT® Assistant - 2018 Issue 11 (November)

Pathology and Laboratory: Surgical Pathology (Q&A) (November 2018)

November 2018 page 11d Pathology and Laboratory: Surgical Pathology Question: What is the correct code to report a human papillomavirus (HPV) high-risk (HR) assay that is a qualitative in situ hybridization (ISH) analysis intended for the use on formalin-fixed, paraffin-embedded (FFPE) tissue stained with an automated staining instrument? The HPV mRNA probes 16, 18, and 33 are combined into one dispenser vial to make a cocktail; one slide is stained; and an interpretation of a positive or negative result is reported. Answer: Code 88365, In situ hybridization (eg, FISH), per specimen; initial single probe stain procedure, should be reported...

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CPT® Assistant content is the official source for CPT® coding guidance. It is an instrumental tool when appealing insurance denials and validating coding to auditors. Monthly issues and an extensive archive provide comprehensive guidance on proper CPT® coding for past, present and upcoming code set releases. Archives date back to 1990 for historical use of codes, changes, rationales, coding tips and trends in the industry.

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